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临床试验/NCT05882383
NCT05882383已完成不适用

Changes of Optical Quality During the Peak of the Covid-19 Pandemic From November 2022 to January 2023 in China

Tianjin Eye Hospital1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2022年11月25日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
110
试验地点
1
主要终点
The value of cornea thickness

研究概览

简要总结

To explore whether cornea structure, and optical quality are affected by the covid-19 infection.

详细描述

Participants with healthy corneas admitted to Tianjin Eye Hospital from November 25 to January 20, 2022 were followed up . At the end of the follow-up, the investigators recorded in detail whether the patients had undergone real-time reverse transcriptase polymerase chain reaction (covid-19 RT-PCR tests) testing, testing time and results. The presence of PCR-positive during follow-up is considered to be covid-19 infection; PCR-Negative and no symptoms of infection during the follow-up period are considered not infected; participants with symptoms but no PCR test were excluded from the study.Participants were divided into three groups according to the RT-PCR results and the presence or absence of symptoms of infection during follow-up. pentacam (Pentacam HR, Oculus, Wetzlar, Germany) was performed during follow-up and the results were recorded,and the data was statistically managed and compared.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 32 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • corneal disease;
  • ocular trauma;
  • Pregnant and lactating women;

结局指标

主要结局

The value of cornea thickness

时间窗: 1 months

The value of cornea thickness from pentacam during follow-up were compared, includig the thinnest point, apex of the cornea.

The value of cornea backscatter

时间窗: 1 months

The value of cornea backscatter from pentacam during follow-up were compared, including anterior layer,central layer and posterior

The value of cornea aberration

时间窗: 1 months

The value of aberration data from pentacam during follow-up were compared, including coma, spherical aberration, defocus, and astigmatism

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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