Changes of Keratometric Value and Ocular Aberration After Treatment of Meibomian Gland Dysfunction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Moderate and Severe Meibomiang Gland Dysfunction (Stage 3 or Stage 4 Meibomiang Gland Dysfunction)
- Sponsor
- Yonsei University
- Primary Endpoint
- Changes of keratometric value and ocular aberration
- Status
- Withdrawn
- Last Updated
- 12 years ago
Overview
Brief Summary
Ocular aberration may play a role in determining optical quality. Recently performed study reported that ocular aberration of preocular tear film would be important factor in not only diagnosing the dry eye but also determining the efficacy of treatment. Therefore, in this study, the investigators will aim to prove the improvement of quality of vision via ocular aberration changes indirectly after the proper treatment for moderate and severe meibomian gland dysfunction. Also, the investigators will evaluate the changes of keratometric values after treatment for moderate and severe meibomian gland dysfunction, which could be demonstrated by autokeratometry, IOLMaster, Pentacam, and iTrace.
Investigators
Eligibility Criteria
Inclusion Criteria
- •(1) stage 3 or 4 meibomian gland dysfunction
Exclusion Criteria
- •history of previous ocular or intraocular surgery
- •ocular infection, non dry eye ocular inflammation, ocular allergy, autoimmune disease,
- •history of intolerance or hypersensitivity to any component of the study medications,
- •wearing contact lenses during the study period, presence of current punctal occlusion,
- •pregnancy, lactating women, and children.
- •Additionally, patients were excluded if they were using any topical ocular or systemic medication that could be used for the treatment MGD or dry eye, including topical or oral antibiotics, topical cyclosporine A, topical or oral steroids, topical non-steroidal anti-inflammatory drugs, topical ocular allergy medications or artificial tears
Outcomes
Primary Outcomes
Changes of keratometric value and ocular aberration
Time Frame: a minimum of four minutes, once or twice dailybefore treatment, after 1 month, and after 2 months of treatment