NCT04226729
Unknown
Not Applicable
Quantitative Assessment of the Vison Using Structural and Functional Indicators and Associations With Brain Function
Sun Yat-sen University1 site in 1 country200 target enrollmentJanuary 25, 2022
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- Sun Yat-sen University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- the visual information processing function
- Last Updated
- 3 years ago
Overview
Brief Summary
Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive impairment. In our study, we aim to quantitatively assess ocular features using structural and functional indicators and define its associations with brain development and intelligence in children.
Investigators
Haotian Lin
Clinical Professor
Sun Yat-sen University
Eligibility Criteria
Inclusion Criteria
- •age from 3 to 12 years old
Exclusion Criteria
- •diagnosed with nervous system disease before
Outcomes
Primary Outcomes
the visual information processing function
Time Frame: recorded at enrollment
collected with the electroencephalogram
best corrected visual acuity
Time Frame: recorded at enrollment
collected with visual acuity chart
Secondary Outcomes
- intraocular pressure(recorded at enrollment)
- refractive status(recorded at enrollment)
- fundus picture(recorded at enrollment)
Study Sites (1)
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