MedPath

Efficacy of topical timolol in acne scars are treating with TCACROSS.

Phase 2
Conditions
Atrophic acne scar.
Scar conditions and fibrosis of skin
L90.5
Registration Number
IRCT20191208045657N1
Lead Sponsor
Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Bilateral facial atrophic acne scars
Minimum age 18 years

Exclusion Criteria

Active acne lesions
Prone to make colloids
Immunocompromised
Active herpes infection
Pregnancy or lactation
Systemic treatment of isotretinoin or immunosuppressant drugs for the past 6 months.
History of sensitivity to any of the materials used in the study
major depression
Patients with low blood pressure and bradycardia or any history of them
History of CHF
History of MI
History of cardiac arrhythmia
Patients with asthma or bronchospasm or or history of them

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
umber of facial atrophic scars. Timepoint: The severity of acne scars is assessed at the beginning of the study, 2 weeks later, and at week 12. Method of measurement: Qualitative Global Scarring Grading System (Goodman and Baron).
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath