Efficacy of oral ketamine in treatment of patients with Major depressive disorder
Not Applicable
- Conditions
- Major Depression.Major Depressive episode
- Registration Number
- IRCT201608071556N93
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
age between 18 –60 years old; moderate to severe major depressive disorder based on Diagnostic & Statistical Mental Disorders (DSM-5); HRSD score above20; signing informed consent. Exclusion criteria: receiving antidepressant drugs within the last month; cardiovascular disease; pregnancy and lactation; receiving ECT (Electroconvulsive Therapy) during the last two months; thyroid disease; alcohol & drug abuse.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Baseline and weeks: 2, 4 and 6 after beginig of treatment. Method of measurement: Hamiltion Depression Rating Scale 17-Item.
- Secondary Outcome Measures
Name Time Method