Evaluation of the use of ketamine medication in the treatment of depressed or bipolar persons

Not Applicable

Recruiting

• Conditions: major depressive disorder, bipolar disorder, suicide risk; F32.9; F31.9

• Registration Number: RBR-472gf3
• Lead Sponsor: Hospital São José

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-07-11
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Volunteers who have any mood disorders and high risk of suicide; 16-59 years old.

Exclusion Criteria

Volunteers manifesting delusions or maniac symptoms to mental status examination or BPRS; an actual history of alcohol or substance dependence with recent use in the last 7 days except nicotine and benzodiazepines; an unstable or untreated medical disorder; severe exogenous intoxication; being pregnant.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction of the depressive symptoms during the intervention period (maximum 14 days) assessed by the instrument Montgomery Asberg Depression Rating Scale (MADRS) from the reduction of at least 50% in pre and post-intervention measurements.

Secondary Outcome Measures

Name	Time	Method
Reduction of suicidal ideation during the intervention period (maximum 14 days) assessed by the instrument Beck Scale for Suicide Ideation (BSI) from the reduction of at least 50% in pre and post-intervention measurements.