Evaluation of the Relationship Between Cardiopulmonary Exercise Testing (CPET ) Abnormalities and Ca-P Status in CKD Stage3-5
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- CPET score change
研究概览
简要总结
Reductions in exercise capacity associated with exercise intolerance augment cardiovascular disease risk and predict mortality in chronic kidney disease. This study utilized cardiopulmonary exercise testing to (a) investigate mechanisms of exercise intolerance; (b) unmask subclinical ca and p and vitamin D abnormalities that may precede cardiovascular disease in chronic kidney disease.
详细描述
Cardiopulmonary exercise testing will carry out in Stage 3-5 chronic kidney disease patients ; estimated glomerular filtration rate <60 ml/min/1.73 m2) and biochemistry will be added (Ca P Via D PTH FGF23).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •CKD Patients with GFR <60 non-dialysis
排除标准
- •not signing consent
- •active coronary disease
结局指标
主要结局
CPET score change
时间窗: 12 MONTHS
Evaluation of CPET score change
Calcium x phosphorus change in stage 3-5
时间窗: 12 MONTHS
CaxP change
次要结局
- Renal Function change(12 MONTHS)
研究者
nooshin dalili
Principal Investigator
Shahid Beheshti University of Medical Sciences