Relationship Between Cardiopulmonary Exercise Testing and Ca-P in Chronic Kidney Disease (CKD)
Completed
- Conditions
- Ckd-Mbd
- Interventions
- Diagnostic Test: CPET
- Registration Number
- NCT04013139
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Reductions in exercise capacity associated with exercise intolerance augment cardiovascular disease risk and predict mortality in chronic kidney disease. This study utilized cardiopulmonary exercise testing to (a) investigate mechanisms of exercise intolerance; (b) unmask subclinical ca and p and vitamin D abnormalities that may precede cardiovascular disease in chronic kidney disease.
- Detailed Description
Cardiopulmonary exercise testing will carry out in Stage 3-5 chronic kidney disease patients ; estimated glomerular filtration rate \<60 ml/min/1.73 m2) and biochemistry will be added (Ca P Via D PTH FGF23).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- CKD Patients with GFR <60 non-dialysis
- age<18
Exclusion Criteria
- HTN
- not signing consent
- active coronary disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description CKD Stage 3 CPET CKD patients with GFR between 30-60cc/min CKD Stage 4 CPET CKD Patients with GFR 15-30 cc/min
- Primary Outcome Measures
Name Time Method Calcium x phosphorus change in stage 3-5 12 MONTHS CaxP change
CPET score change 12 MONTHS Evaluation of CPET score change
- Secondary Outcome Measures
Name Time Method Renal Function change 12 MONTHS GFR change
Trial Locations
- Locations (1)
Nooshin Dalili
🇮🇷Tehran, Iran, Islamic Republic of