utritional Intervention for Preterm Infants-2
- Conditions
- Preterm neonates, Premature infants, parenteral nutrition, tolerance
- Registration Number
- NL-OMON20272
- Lead Sponsor
- Erasmus Medical Center - Sophia Children's Hospital
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 240
Inclusion Criteria
1. Inborn, Gestational weight less than 1500g
Exclusion Criteria
1. Congenital anomalies
2. Metabolic disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method itrogen balance
- Secondary Outcome Measures
Name Time Method 1. Safety of the nutritional regimen: as reflected by normal blood chemistry, no effect on hearing ability, no effect on chronic lung disease; <br /><br>2. Growth: measured in terms of body weight, knemometry, head circumference, protein accretion and protein breakdown; <br /><br>3. Fatty acid profile in plasma and erythrocytes; <br /><br>4. Energy expenditure;<br /> <br>5. Short- and long-term outcome: days on mechanical ventilation, incidence of bronchopulmonary dysplasia, incidence of infection, intraventricular hemorrhage, and necrotizing enterocolitis, normal ALGO-test and Bayley III scores