earn to move 0-2 years: early intervention in children with cerebral palsy.

Recruiting

Lead Sponsor: Prof. dr. M. Hadders-AlgraUniversity Medical Centre GroningenDevelopmental Neurology (Postbox CA85)PO Box 30.0019700 RB GroningenThe Netherlands.Tel: +31 50 3614252Email: M.Hadders-Algra@med.umcg.nl

Brief Summary: Blauw-Hospers CH, De Graaf-Peters VB, Dirks T, Bos AF, Hadders-Algra M. Does early intervention in infants at high risk for a developmental motor disorder improve motor and cognitive development? Neurosci Biobehav Rev 2007a; 31: 1201-12. <br> - Dirks T, Hadders-Algra M. COPCA – Coping with and Caring for infants with neurological dysfunction – a family centered program. Handleiding, nog niet officiëel uitgeven, 2003.<br> - Hadders-Algra M. The Neuronal Group Selection Theory: an attractive framework to explain variation in normal motor development. Dev Med Child Neurol 2000a; 42: 566-72.<br> - Hadders-Algra M. The Neuronal Group Selection Theory: promising principles for understanding and treating developmental motor disorders. Dev Med Child Neurol 2000b; 42: 707-15.

Recruitment & Eligibility

Inclusion Criteria

1. Infants (3-9 months corrected age) at very high risk for CP or with CP and their families.

2. Participating caregivers must have sufficient comprehension of the Dutch language.

Exclusion Criteria

1. Children with additional severe congenital disorders, such as serious congenital heart disorder

Primary Outcome Measures

Name	Time	Method
Motor performance as measured by the Infant Motor Profile (IMP).

Secondary Outcome Measures

Name	Time	Method
- Neurological condition according to Touwen<br>Infant motor skills as measured with AIMS, GMFM, and Bayley Scales, Psychomotor Development Index.<br /><br><br>- Cognitive development as measured with Bayley Scales, Mental Development Index.<br /><br><br>- Daily life functioning as measured with the VABS and PEDI.<br /><br><br>- Quality of life as measured with the ITQOL.<br /><br><br>- Family related outcomes: video-analysis of caregiver's behaviour, UCL, NOSI-K, MPOC, FES.<br /><br><br>- Working mechanisms: postural control by means of multiple surface EMG recordings and Kinematics. Assesment of actual contents of COPCA and TPP sessions by means of video recordings. Weekly diaries and DAIS.