Biomarker study in bariatric surgery patients with and without obstructive sleep apnea

• Conditions: Morbide obesitas, bariatrische chirurgie, OSAS; Obstructive sleep apnea; airway collaps; 10046304; 10017998

• Registration Number: NL-OMON42714
• Lead Sponsor: Sint Lucas Andreas Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 2019-04-17
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 135

Inclusion Criteria

Patients scheduled for primary laparoscopic roux-en-y gastric bypass (LRYGB) or primary laparoscopic sleeve gastrectomy (LSG)

Exclusion Criteria

Other bariatric surgical procedures than LRYGB or LSG, such as laparoscopich gastric banding or revisional surgery

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Which biomarkers have a good agreement with PSG results, preoperatively?<br /><br>Could these biomarkers distinguish OSA/non-OSA patients, and<br /><br>no/mild/moderate/severe OSA patients? </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>2. What is the effect of bariatric surgery on these OSA associated biomarkers?<br /><br>3. Are there biomarkers that predict the amelioration of OSA after bariatric<br /><br>surgery?<br /><br>4. What is the relationship between OSA associated biomarkers, weight loss and<br /><br>other weight associated existing comorbidities including type II diabetes,<br /><br>hypertension and dyslipidemia? Including medication use.</p><br>