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Role of prophylactic microbial supplements in prevention of blood stream infection and intestinal tract injury in premature neonates

Not Applicable
Conditions
Health Condition 1: null- 1. Necrotising enterocolitis 2. Nosocomial sepsis
Registration Number
CTRI/2018/04/013401
Lead Sponsor
Gousia mukhtar
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

All infants admitted to our nicu with birth weight less than 2 kg or gestational age less than 35 weeks as assessed by EDD and further confirmed by Ballards score who survive the first 24 hrs of life will be enrolled in the study.

Exclusion Criteria

1. sepsis

2. Major congenital anomalies

3. Severe asphyxia

4. Severe IUGR

5. Immunocompromised host like hiv infected infants

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To compare the safety and efficacy of prophylactic probiotics versus no treatment in prevention of <br/ ><br>1.Necrotising colitis <br/ ><br>2. Nosocomial sepsis <br/ ><br>In preterm low birth weight babiesTimepoint: 1st of june 2018
Secondary Outcome Measures
NameTimeMethod
1. Duration of hospitalization <br/ ><br>2. Time to establish full feeds <br/ ><br>3.Episodes of feed intolerance <br/ ><br>4. All cause neonatal mortalityTimepoint: 1st of june, 2018
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