Skip to main content
Clinical Trials/NCT05748457
NCT05748457
Enrolling By Invitation
Not Applicable

Changes in Outcomes of Treatment for Adolescent Anorexia Nervosa After Implementation of Family Based Treatment in a Norwegian Child and Adolescent Mental Health Service: A Retrospective Cohort Study With Prospective Follow-up

University Hospital, Akershus1 site in 1 country175 target enrollmentMarch 27, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anorexia Nervosa
Sponsor
University Hospital, Akershus
Enrollment
175
Locations
1
Primary Endpoint
Time to weight restoration
Status
Enrolling By Invitation
Last Updated
2 years ago

Overview

Brief Summary

The goal of this observational study is to compare short and long-term effects of manualised Family Based Treatment for adolescent anorexia nervosa to those of non-manualised family therapy. The study will approach former patients who were treated before and after Family Based Therapy was adopted in an outpatient clinic, and extract data from electronic health records and public registries.

Detailed Description

A two-group retrospective exploratory cohort study with longitudinal follow-up comparing adolescents with anorexia nervosa treated with generic family therapy to those treated with the manualised Family Based Treatment (FBT). The primary aim is to investigate whether adoption of FBT has led to faster normalisation of weight and lower rates of eating disorder in early adulthood. Secondary aims are to investigate whether implementation of FBT has changed the time to discharge, heterogeneity of patient weight change across treatment, rates of adverse events, rates of readmission, patient experiences of the treatment, long term functional outcomes and mortality. Data are extracted from patient health records, reported by participants and extracted from public registries.

Registry
clinicaltrials.gov
Start Date
March 27, 2023
End Date
December 2042
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Akershus
Responsible Party
Principal Investigator
Principal Investigator

Erling W. Rognli

Psykologspesialist

University Hospital, Akershus

Eligibility Criteria

Inclusion Criteria

  • Clinical diagnosis of F50.0 Anorexia nervosa or F50.1 Atypical anorexia nervosa according to the International Classification of Diseases-10.

Exclusion Criteria

  • Patient was treated during the years 2018-2020 and FBT was never initiated according to patient health records.

Outcomes

Primary Outcomes

Time to weight restoration

Time Frame: Assessed retrospectively at enrolment.

Number of days from start of treatment to a weight measurement placing the patient at or above 95% of expected body weight (50. percentile) for age and sex given Norwegian population norms.

Secondary Outcomes

  • Time to discharge from treatment(Assessed retrospectively at enrolment.)
  • Treatment for eating disorder in adulthood(Assessed 5, 10, 15 and 20 years post treatment.)
  • Mortality(Assessed 5, 10, 15 and 20 years post treatment.)
  • Employment status and welfare benefits(Assessed 5, 10, 15 and 20 years post treatment.)
  • Time to readmission to treatment(Assessed retrospectively at enrolment.)
  • Level of education(Assessed 5, 10, 15 and 20 years post treatment.)

Study Sites (1)

Loading locations...

Similar Trials