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Clinical Trials/DRKS00028994
DRKS00028994
Recruiting
未知

Coronary CT Angiography for Guiding Percutaneous Coronary Artery Intervention: a Prospective Randomised Study - CT-PCI TRIA

niversitätsklinikum Erlangen Medizinische Klinik 20 sites240 target enrollmentMay 9, 2022

Overview

Phase
未知
Intervention
Not specified
Conditions
I25
Sponsor
niversitätsklinikum Erlangen Medizinische Klinik 2
Enrollment
240
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 9, 2022
End Date
TBD
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversitätsklinikum Erlangen Medizinische Klinik 2

Eligibility Criteria

Inclusion Criteria

  • 1\.Subjects must be at least 18 years of age.
  • 2\.Available coronary CT angiography data set
  • 3\.Obstructive coronary artery disease with at least one lesion causing \> 50% stenosis in a coronary segment planned for percutaneous revascularisation according to clinical decision making.
  • 4\.Evidence of myocardial ischemia e.g. stable angina, silent ischemia, unstable angina suitable for elective PCI.
  • 5\.Good CT image quality with absence of artefacts in the affected coronary segment
  • 6\.No more than 2 target lesions requiring PCI are present in any single vessel, and no more than 2 target vessels are allowed. (PCI to non\-target vessels are allowed after 48 hours of index PCI).
  • 7\.The patient signing a written informed consent.

Exclusion Criteria

  • 1\. Age \>85 years
  • 2\. Target lesion location in a previously revascularized segment (stents or coronary artery bypass grafting)
  • 3\. Left main coronary artery stenosis
  • 4\. Patients with status post complicated PCI
  • 5\. Cardiogenic shock or hemodynamic instability
  • 6\. Creatinine clearance \< 30 ml/l/min/1\.73 m² as calculated by MDRD formula and not on dialysis.
  • 7\. Left ventricular ejection fraction \< 30%
  • 8\. Planned cardiac or non\-cardiac surgery within 24 months after index procedure
  • 9\. Prior PCI within the target vessel(s) within 12 months.
  • 10\. Any prior PCI in a non\-target vessel within 24 hours before study or within 30 days if unsuccessful or complicated.

Outcomes

Primary Outcomes

Not specified

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