Coronary CT Angiography for Improved Assessment of Suspected Acute Coronary Syndrome with Inconclusive Diagnostic Work-up - COURSE

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Observational non invasive

Sponsor

•Patients eligible for inclusion are aged between 30 and 80 years and present to the emergency department with symptoms suggestive of non\-ST elevation acute coronary syndrome. These patients have a normal or non\-diagnostic ECG. High\-sensitivity levels are slightly elevated but under the limit for definitive diagnosis of acute myocardial infarction. During serial sampling there is no more than 40% rise or fall.

•Inability or unwillingness to provide informed consent.
•History of proven CAD, defined as documented prior myocardial infarction, percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery.
•Previous examination with either invasive angiography or CCTA in the last 3 years.
•Clinical instability: clinical heart failure, hemodynamic instability, severe chest pain.
•CCTA¬\-specific contra¬indications:
•o Allergy to iodine contrast media
•o Pregnancy
•o Impaired renal function: estimated glomerular filtering rate \<45 ml/min
•o Severe arrhythmia likely to affect image interpretation
•o BMI \> 40 kg/m2