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Clinical Trials/NCT05442242
NCT05442242
Not Yet Recruiting
N/A

Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis (UNIKORN): a Study Protocol of a Randomized Controlled Trial

Töölö Hospital0 sites100 target enrollmentNovember 2022
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ConditionsKnee Osteoarthritis

Overview

Phase
N/A
Intervention
Not specified
Conditions
Knee Osteoarthritis
Sponsor
Töölö Hospital
Enrollment
100
Primary Endpoint
KOOS
Status
Not Yet Recruiting
Last Updated
3 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

Unicompartmental knee arthroplasty (UKA) and High Tibial Osteotomy are both valid treatment options for isolated medial knee osteoarthritis. Literature to date is lacking high grade evidence of the outcomes between these procedures. This is a study protocol for randomized controlled trial comparing UKA vs HTO in late stage medial knee osteoarthritis.

Registry
clinicaltrials.gov
Start Date
November 2022
End Date
December 2025
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Töölö Hospital
Responsible Party
Principal Investigator
Principal Investigator

Juuso Siren

Principal Investigator

Töölö Hospital

Eligibility Criteria

Inclusion Criteria

  • •Isolated KL 3-4 medial knee arthrosis
  • •Varus \> 3 degrees
  • •Age 45-65 years

Exclusion Criteria

  • •Post-traumatic arthrosis
  • •Arthrosis in the lateral compartment more than KL grade I in MRI
  • •Post- traumatic arthrosis
  • •Instability
  • •Malignancy Obesity

Outcomes

Primary Outcomes

KOOS

Time Frame: 1- year

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