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Clinical Trials/NCT06715917
NCT06715917
Active, not recruiting
Not Applicable

PROSPECTIVE, MULTICENTRE POST-MARKETING SURVEILLANCE STUDY to ASSESS PERFORMANCE of the GMK UNI ANATOMICAL CEMENTLESS IMPLANT

Medacta International SA5 sites in 2 countries249 target enrollmentMarch 6, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoarthritis of the Knee
Sponsor
Medacta International SA
Enrollment
249
Locations
5
Primary Endpoint
New Knee Society Score (KSS)
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

Unicompartmental Knee Arthroplasty (UKA) is the principal surgical alternative to Total Knee Arthroplasty (TKA) in patients with end-stage unicompartmental tibiofemoral osteoarthritis (OA) of the knee. The current post-marketing surveillance study aims to monitor GMK-UNI monocompartmental knee prosthesis performances over a 10-year time period.

Registry
clinicaltrials.gov
Start Date
March 6, 2017
End Date
March 6, 2032
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients presenting with disease that meets the indications for use for Medacta implants included in this study (on-label use);
  • Patients who are willing and able to provide written informed consent for participation in the study. Written informed consent must be obtained prior to the patient's surgery;
  • Patient's age between 18 and 75 years old;
  • Patients must be willing to comply with the pre and postoperative evaluation schedule.

Exclusion Criteria

  • Patients with one or more medical conditions identified as a contraindication defined by the labelling on any Medacta implants used in this study;
  • Any patient who cannot or will not provide informed consent for participation in the study;
  • Patients who need a revision surgery
  • Patients unable to understand and take action;
  • Any case not described in the inclusion criteria;
  • Patients aged under 18 years;
  • Patients aged over 75 years;

Outcomes

Primary Outcomes

New Knee Society Score (KSS)

Time Frame: Preoperative, 3 months, 1, 2, 3, 5, 7 and 10 years

The new Knee Society Knee Scoring System is both physician and patient derived. It includes versions to be administered preoperatively and postoperatively. It has an initial assessment of demographic details, including an expanded Charnley functional classification. The objective knee score, completed by the surgeon, includes a VAS score of pain walking on level ground and on stairs or inclines, as well as an assessment of alignment, ligament stability, and ROM, along with deductions for flexion contracture or extensor lag. Patients then record their satisfaction, functional activities, and expectations. Given the diverse activity profiles of many contemporary patients, the functional component of the score was improved to include a patient-specific survey, which evaluates features such as standard activities of daily living, patient-specific sports and recreational activities, patient satisfaction, and patient expectations

Secondary Outcomes

  • Kujala Score(3 months, 1, 2, 3, 5, 7 and 10 years)
  • Survival of the implant(3 months, 1, 2, 3, 5, 7 and 10 years)
  • Safety of the implant(Intraoperative, 3 months, 1, 2, 3, 5, 7 and 10 years)

Study Sites (5)

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