Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis (UNIKORN): a Study Protocol of a Randomized Controlled Trial

Not Applicable

Not yet recruiting

• Conditions: Knee Osteoarthritis
• Interventions: Procedure: Unicompartmental knee arthroplasty; Procedure: High tibial osteotomy

• Registration Number: NCT05442242
• Lead Sponsor: Töölö Hospital

Brief Summary

Unicompartmental knee arthroplasty (UKA) and High Tibial Osteotomy are both valid treatment options for isolated medial knee osteoarthritis. Literature to date is lacking high grade evidence of the outcomes between these procedures. This is a study protocol for randomized controlled trial comparing UKA vs HTO in late stage medial knee osteoarthritis.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-06-28
• Study First Submitted QC: 2022-06-28
• Status Verified: 2022-07
• Study First Posted: 2022-07-01
• Last Update Submitted: 2022-07-01
• Last Update Posted: 2022-07-06
• Study Start: 2022-11
• Primary Completion: 2024-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Isolated KL 3-4 medial knee arthrosis
• Varus > 3 degrees
• Age 45-65 years

Exclusion Criteria

• Post-traumatic arthrosis
• Arthrosis in the lateral compartment more than KL grade I in MRI
• Post- traumatic arthrosis
• Instability
• Malignancy Obesity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Unicompartmental knee osteoarthritis	Unicompartmental knee arthroplasty	-
High tibial osteotomy	High tibial osteotomy	-

Primary Outcome Measures

Name	Time	Method
KOOS	1- year