Comparison of TIVA (Total Intravenous Anesthesia) and TIVA Plus Palonosetron in Preventing Postoperative Nausea and Vomiting
Not Applicable
Completed
- Conditions
- Postoperative Nausea and Vomiting
- Interventions
- Drug: Total intravenous anesthesia
- Registration Number
- NCT01478165
- Lead Sponsor
- Incheon St.Mary's Hospital
- Brief Summary
A total intravenous anesthesia (TIVA) is a useful anesthetic technique that reduces the incidence of postoperative nausea and vomiting (PONV).
Investigator hypothesized the incidence of PONV can be further reduced when palonosetron is added to TIVA.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- ASA Physical Status 1 or 2
- Elective gynaecological laparoscopic surgery of ≥ 1h duration
Exclusion Criteria
- Anti-emetics, steroids, or psychoactive medications within 24 h of study initiation
- Vomiting or retching in the 24 h preceding surgery
- Cancer chemotherapy within 4 weeks or emetogenic radiotherapy within 8 weeks before study entry
- Ongoing vomiting from gastrointestinal disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Tiva group (Group T) Total intravenous anesthesia - TIVA plus palonosetron group (Group T+P) Total intravenous anesthesia plus palonosetron -
- Primary Outcome Measures
Name Time Method Incidence of postoperative nausea and vomiting For 24 hours after surgery
- Secondary Outcome Measures
Name Time Method Severity of nausea For 24 hours after surgery
Trial Locations
- Locations (1)
Incheon St. Mary's hospital
🇰🇷Incheon, Korea, Republic of