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Comparison of Two Types of General Anesthesia, Venous versus Inhalatory, regarding the Risk of Renal Injury after Videolaparoscopic Obesity Surgery

Phase 4
Conditions
Acute renal failure, morbid obesity
C18.654.726.500.700
C12.777.419.780.050
Registration Number
RBR-8wt2fy
Lead Sponsor
Adriano Teixeira Fernandes
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Data analysis completed
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

morbidly obese patients, scheduled for video laparoscopic bariatric surgery; both gender; age between 18 and 65 year.

Exclusion Criteria

volunteers with lung disease; heart failure; renal failure; cancer of any etiology; patients on chronic corticosteroid use; that are not available to participate in all stages of the study.

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Expected primary outcome - Difference of 33% on average values of serum lipocalin 2 (NGAL) during the perioperative period of video laparoscopic bariatric surgery between the two groups of general anesthesia;Observed primaryoutcome - We did not find significant differences in serum lipocalin between the groups for general anesthesia during the procedure
Secondary Outcome Measures
NameTimeMethod
Expected secondary outcomes - Change in the rate of acute renal injury, evidenced by clinical and laboratory markers (urine output and serum creatinine, translated into RIFLE criteria) in the perioperative period of laparoscopic bariatric surgery according to the type of anesthesia used;Secondary outcomes observed - We did not find significant differences in the rates of acute kidney injury defined by clinical and laboratory criteria (RIFLE criteria) between the two groups of general anesthesia in the perioperative period of laparoscopic bariatric surgery
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