Comparing anaesthesia given through veins and anaesthesia given through lungs for post operative confusion and memory loss
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/03/032265
- Lead Sponsor
- SCTIMST fluid research grant
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age from 18 -80 yrs
2.Undergoing CABG or Aortic valve surgery for Aortic stenosis on CPB
3.Consenting for the study
Exclusion Criteria
emegency surgery, poor language comprehension, neurologic disorders, allergy to anaesthetic agent,significant carotid artery stenosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Compare the incidence of early postoperative delirium on post opeative day 1 and 2 in both the groups <br/ ><br>2.Compare the cerebral oxygen saturation in both the groupsTimepoint: 1.Compare the incidence of early postoperative delirium in both the groups on post operative days 1 and 2 <br/ ><br>2.Compare the cerebral oxygen saturation in both the groups baseline before induction,after intubation induction,immediately after <br/ ><br>going on cardiopulmonary bypass,after aortic cross clamp,at moderate hypothermia(28�°c),during rewarming,after cpb and after sternal closure
- Secondary Outcome Measures
Name Time Method 1.Intraoperative glycaemic control in both the groups <br/ ><br>2.Analyse the Katz 3-5 atherosclerosis in the patients with post op delirium. <br/ ><br> 3.Analyse incidence of early post-operative cognitive dysfunction in both the groupsTimepoint: 1.Blood glucose baseline at start of case,after going on cpb and immideately after coming off CPB <br/ ><br>2.Preoperative TEE KATZ score done after intubation <br/ ><br>3.MOCA score for post operative cognitive dysfunction assessment day before surgery and on post operative day 7