A clinical trial to study the effect of two methods of anesthesia, total intravenous anesthesia and inhalational anesthesia on neuroinflammatio
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/10/058436
- Lead Sponsor
- Sree Chitra Thirunal Institute of Medical Sciences and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patient consent
2) ASA class I-II
3)Age 18-65 years, undergoing craniotomy for supratentorial glioma in the neurosurgery operation theatre
4)Preoperative Karnofsky Performance Scale of 70 or above
Exclusion Criteria
1) ASA class III,IV, V
2) Severe or uncompensated cardiovascular, renal, hepatic or endocrine disease
3) Pregnancy, postpartum and lactating females
4) Drug allergy to Propofol
5) Refusal to consent by patient or next of kin
•patients with an active inflammatory process such as infection or immunologic illness known to increase the baseline immunologic markers,
•Emergency surgery
•Revision craniotomy at the same site
•Preoperative history of seizures.
• h/o preoperative cognitive dysfunction
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method