MedPath

Evaluation of the Dosing Regimen of Vancomycin in Pediatric Patients

Completed
Conditions
Gram-Positive Bacterial Infections
Interventions
Other: Plasma exposure vancomycin
Registration Number
NCT03560440
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Brief Summary

In this retrospective registry the investigators wish to verify whether the current dosing regime of vancomycin is leading to the appropriate pharmacokinetic targets in pediatric patients. Therefore data will be collected from all pediatric patients hospitalized in University Hospitals Leuven between January 2012 and April 2014 who were treated with vancomycine.

Detailed Description

In this retrospective registry the investigators wish to verify whether the current dosing regime of vancomycin is leading to the appropriate pharmacokinetic targets in pediatric patients. Therefore data will be collected from all pediatric patients hospitalized in University Hospitals Leuven between January 2012 and April 2014 who were treated with vancomycine. Patient files will be screened for relevant information. Individual patients can be included multiple times if vancomycin has been administered more than once.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
368
Inclusion Criteria
  • Pediatric patients hospitalized in the University Hospitals Leuven between January 2012 and April 2014, treated with vancomycin
Exclusion Criteria

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Plasma exposure vancomycinPlasma exposure vancomycinPediatric patients treated with vancomycin
Primary Outcome Measures
NameTimeMethod
Loading dose related plasma exposure vancomycin24 hours after loading dose

Plasma exposure to vancomycin in relation to administered dose

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

UZ Leuven

🇧🇪

Leuven, Belgium

© Copyright 2025. All Rights Reserved by MedPath