MedPath

Diaphragmatic and Pulmonary US for Extubation Success Prediction

Completed
Conditions
Airway Extubation
Registration Number
NCT02799056
Lead Sponsor
Hospital Universitario Dr. Jose E. Gonzalez
Brief Summary

The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.

Detailed Description

The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit. The investigators' null hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound can not predict the success of extubation in adult patients hospitalized in the intensive care unit.

The alternative hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.

The study is a no experimental study of diagnostic test, prospective with longitudinal capture. The study will consist of two parts: the first with the aim of finding the values best combination of sensitivity and specificity compared to extubation success for diaphragmatic shortening fraction and the number of lung quadrants with lines B. In the second part the study will make the prospective validation of these values.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
82
Inclusion Criteria
  • 18 years of older
  • Hospitalized in medical or surgical intensive care unit
  • Successful spontaneous ventilation trial
Exclusion Criteria
  • Patients reintubated after a first failure after extubation
  • Injuries to prevent conduct ultrasound
  • Pregnancy
  • History of neuromuscular disease
  • Brain injury that prevented adequate protection of the airway (Glasgow Coma Scale <8)
  • Unilateral or bilateral Pneumothorax
  • Presence of chest tube in right hemothorax
  • Right subphrenic abscess
  • Known uni- or bilateral phrenic nerve injury
  • Unilateral or bilateral diaphragmatic Paralysis
  • Unwillingness of the patient or guardian to participate in the study

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Extubation success72 h after extubation

The investigators consider successful extubation when the patient does not require reintubation within 72 hours of its extubation

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

UANL University Hospital

🇲🇽

Monterrey, Nuevo León, Mexico

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