Diaphragmatic Shortening Fraction and Pulmonary Ultrasound Combined Analysis for Extubation Success Prediction in Critical Care Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- Extubation success
研究概览
简要总结
The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.
详细描述
The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit. The investigators' null hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound can not predict the success of extubation in adult patients hospitalized in the intensive care unit.
The alternative hypothesis is the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation in adult patients hospitalized in the intensive care unit.
The study is a no experimental study of diagnostic test, prospective with longitudinal capture. The study will consist of two parts: the first with the aim of finding the values best combination of sensitivity and specificity compared to extubation success for diaphragmatic shortening fraction and the number of lung quadrants with lines B. In the second part the study will make the prospective validation of these values.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years of older
- •Hospitalized in medical or surgical intensive care unit
- •Successful spontaneous ventilation trial
排除标准
- •Patients reintubated after a first failure after extubation
- •Injuries to prevent conduct ultrasound
- •Pregnancy
- •History of neuromuscular disease
- •Brain injury that prevented adequate protection of the airway (Glasgow Coma Scale <8)
- •Unilateral or bilateral Pneumothorax
- •Presence of chest tube in right hemothorax
- •Right subphrenic abscess
- •Known uni- or bilateral phrenic nerve injury
- •Unilateral or bilateral diaphragmatic Paralysis
- •Unwillingness of the patient or guardian to participate in the study
结局指标
主要结局
Extubation success
时间窗: 72 h after extubation
The investigators consider successful extubation when the patient does not require reintubation within 72 hours of its extubation
次要结局
未报告次要终点
研究者
Julio Edgardo González Aguirre
Dr.
Hospital Universitario Dr. Jose E. Gonzalez