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临床试验/CTRI/2024/07/070622
CTRI/2024/07/070622尚未招募不适用

The Effect Of Anthropometric Parameters On Subarchnoid Block Characteristics And Hemodynamics In Parturients Undergoing Lower Segment Cesarean Section (LSCS)- A Prospective Observational Study

Rajarajeswari Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 58 人开始时间: 2024年7月26日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
58
试验地点
1
主要终点
To determine the effects of the anthropometric parameters on the spread of spinal anaesthesia with respect to time taken to achieve T4 level and the maximum level blockade achieved by finding the correlation coefficient.

研究概览

简要总结

When selecting the anesthesia method in cesarean operations, attention must be paid to the

urgency of the operation, pre-existing maternal systemic problems, general status of the

fetus,and the surgeon’s and patient’s preference. Although general or regional anaesthesia

can be used in lower segment Caesarean section (LSCS), regional anesthesia is the most

widely preferred anaesthesia method for caesarean sections in developed countries.

Regional anaesthesia offers many advantages to the mother like,awake mother during the

labour, very little or no requirement for airway intervention, protection of airway reflexes,

reduced blood loss, reduced probability of drug-related fetal depression, and the

continuation of analgesia in the postoperative period.

There is a greater tendency of high level of sensory blockade in parturients with spinal

anaesthesia. Pregnant patients display higher sensitivity to local anaesthetics. Neuraxial

blockage forms at low concentration of local anaesthetics. A decreased lumbosacral

subarachnoidal space volume is a major factor in the cephalad intrathecal spread of local

anesthetics in term parturients and their subarachnoidal space is decreased due to the

compressive effect of huge uterus.

There is greater amount of epidural tissue in parturients, the epidural veins are widened and

the epidural space is narrowed, therefore there is a need for 25-30% less local anaesthetics

in spinal and epidural anaesthesia. In circumstances that lead to increased intra abdominal

pressure or widening of epidural veins, generally high levels of blocks are induced.

Abdominal circumference(AC) correlates with intra abdominal volume, maternal AC

increases during pregnancy and it is influenced by fetus size, amniotic fluid, size of the

uterus.

Increased height of block can lead to high spinal anaesthesia, hypotension and respiratory

depression. However, low level of blockade can lead to inadequate anesthesia and patient

discomfort. Although it is considered safe anaesthetic method, nausea and vomiting are

reported after spinal anaesthesia despite prehydration and left displacement of uterus. This

is attributed to greater aortio caval compression and greater cephaloid spread of sensory blockade by an enlarged uterus.

Hence various parturient factors such as height, body mass index(BMI), body surface

area(BSA), abdominal circumference (AC), Waist hip ratio, symphysis fundal height

(SFH), baby weight, vertebral column length may influence the spread of spinal anaesthesia

and have been studied individually to know their effects with variable results.

Hence we planned a study to know the effect of the anthropometric factors on the block

characteristics after subarachnoid block in parturients undergoing elective LSCS.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
Female

入选标准

  • Parturients with American Society of Anesthesiologists(ASA)1 and 2 status undergoing elective LSCS under sub arachnoid block and willing to give consent will be included.

排除标准

  • Parturients undergoing LSCS under general anaesthesia.
  • Parturients undergoing emergency LSCS.
  • Patients receiving intrathecal additives.
  • Any contraindication to spinal Anaesthesia.
  • Multiple gestation,gestational diabetes mellitus,polyhydramnios.
  • History of spinal deformity or spine surgery.
  • Patients refusing to participate in the study.

结局指标

主要结局

To determine the effects of the anthropometric parameters on the spread of spinal anaesthesia with respect to time taken to achieve T4 level and the maximum level blockade achieved by finding the correlation coefficient.

时间窗: 0,1,2,3,4,5,7,9,11,13,15 minutes

次要结局

  • To determine the effects of the anthropometric measurements on heart rate and blood pressure.(To compare the drug dose given conventionally with height weight based formula.)

研究者

申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Niveditha S

Rajarajeswari Medical College and Hospital

研究点 (1)

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