The Effect Of Anthropometric Parameters On Subarchnoid Block Characteristics And Hemodynamics In Parturients Undergoing Lower Segment Cesarean Section (LSCS)- A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- To determine the effects of the anthropometric parameters on the spread of spinal anaesthesia with respect to time taken to achieve T4 level and the maximum level blockade achieved by finding the correlation coefficient.
研究概览
简要总结
When selecting the anesthesia method in cesarean operations, attention must be paid to the
urgency of the operation, pre-existing maternal systemic problems, general status of the
fetus,and the surgeon’s and patient’s preference. Although general or regional anaesthesia
can be used in lower segment Caesarean section (LSCS), regional anesthesia is the most
widely preferred anaesthesia method for caesarean sections in developed countries.
Regional anaesthesia offers many advantages to the mother like,awake mother during the
labour, very little or no requirement for airway intervention, protection of airway reflexes,
reduced blood loss, reduced probability of drug-related fetal depression, and the
continuation of analgesia in the postoperative period.
There is a greater tendency of high level of sensory blockade in parturients with spinal
anaesthesia. Pregnant patients display higher sensitivity to local anaesthetics. Neuraxial
blockage forms at low concentration of local anaesthetics. A decreased lumbosacral
subarachnoidal space volume is a major factor in the cephalad intrathecal spread of local
anesthetics in term parturients and their subarachnoidal space is decreased due to the
compressive effect of huge uterus.
There is greater amount of epidural tissue in parturients, the epidural veins are widened and
the epidural space is narrowed, therefore there is a need for 25-30% less local anaesthetics
in spinal and epidural anaesthesia. In circumstances that lead to increased intra abdominal
pressure or widening of epidural veins, generally high levels of blocks are induced.
Abdominal circumference(AC) correlates with intra abdominal volume, maternal AC
increases during pregnancy and it is influenced by fetus size, amniotic fluid, size of the
uterus.
Increased height of block can lead to high spinal anaesthesia, hypotension and respiratory
depression. However, low level of blockade can lead to inadequate anesthesia and patient
discomfort. Although it is considered safe anaesthetic method, nausea and vomiting are
reported after spinal anaesthesia despite prehydration and left displacement of uterus. This
is attributed to greater aortio caval compression and greater cephaloid spread of sensory blockade by an enlarged uterus.
Hence various parturient factors such as height, body mass index(BMI), body surface
area(BSA), abdominal circumference (AC), Waist hip ratio, symphysis fundal height
(SFH), baby weight, vertebral column length may influence the spread of spinal anaesthesia
and have been studied individually to know their effects with variable results.
Hence we planned a study to know the effect of the anthropometric factors on the block
characteristics after subarachnoid block in parturients undergoing elective LSCS.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)(—)
- 性别
- Female
入选标准
- •Parturients with American Society of Anesthesiologists(ASA)1 and 2 status undergoing elective LSCS under sub arachnoid block and willing to give consent will be included.
排除标准
- •Parturients undergoing LSCS under general anaesthesia.
- •Parturients undergoing emergency LSCS.
- •Patients receiving intrathecal additives.
- •Any contraindication to spinal Anaesthesia.
- •Multiple gestation,gestational diabetes mellitus,polyhydramnios.
- •History of spinal deformity or spine surgery.
- •Patients refusing to participate in the study.
结局指标
主要结局
To determine the effects of the anthropometric parameters on the spread of spinal anaesthesia with respect to time taken to achieve T4 level and the maximum level blockade achieved by finding the correlation coefficient.
时间窗: 0,1,2,3,4,5,7,9,11,13,15 minutes
次要结局
- To determine the effects of the anthropometric measurements on heart rate and blood pressure.(To compare the drug dose given conventionally with height weight based formula.)
研究者
Dr Niveditha S
Rajarajeswari Medical College and Hospital
