The Effect of Intra-abdominal Pressure and Abdominal Circumference on Sensory Block Level After Spinal Anesthesia in Pregnant Women Undergoing Cesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 107
- 试验地点
- 1
- 主要终点
- Maximum sensory block level after spinal anesthesia
研究概览
简要总结
Spinal anesthesia is commonly used for cesarean section and provides effective anesthesia with rapid onset. However, the spread of spinal anesthesia may vary among pregnant women due to physiological and anatomical changes during pregnancy. Increased intra-abdominal pressure and abdominal circumference may influence cerebrospinal fluid dynamics and affect the level of sensory block achieved after spinal anesthesia.
This prospective observational study aims to evaluate the relationship between intra-abdominal pressure, abdominal circumference, and the maximum sensory block level following spinal anesthesia in pregnant women undergoing cesarean section. Intra-abdominal pressure and abdominal circumference will be measured before surgery, and sensory block levels and hemodynamic parameters will be assessed after spinal anesthesia. The findings of this study may help to better understand factors affecting spinal block spread in pregnant patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women aged 18-40 years
- •Scheduled for elective cesarean section at Kütahya City Hospital
- •Planned spinal anesthesia
- •ASA physical status II-III
- •Provided written informed consent
排除标准
- •Refusal to participate in the study
- •Emergency cesarean section
- •Preeclampsia or other hypertensive disorders of pregnancy
- •Onset of labor or premature rupture of membranes
- •Clinical conditions affecting intra-abdominal pressure, including peripheral edema or ascites
- •Height <140 cm or >180 cm
- •Body mass index < 40 kg/m²
- •Spinal deformity or history of spinal surgery
- •Contraindications to neuraxial anesthesia
- •Known allergy to bupivacaine
- •Requirement for additional surgical procedures other than cesarean section
- •Conditions contraindicating or interfering with intra-abdominal pressure measurement, including active or previous postdural puncture headache, neurogenic bladder, hematuria, or incidental abdominal mass
结局指标
主要结局
Maximum sensory block level after spinal anesthesia
时间窗: Within the first 30 minutes after spinal anesthesia
The maximum dermatomal level of sensory block assessed by loss of cold sensation after spinal anesthesia.
次要结局
- Intra-abdominal pressure(Baseline (preoperative, before spinal anesthesia) and early postoperative period (within 30 minutes after cesarean section))
- Abdominal circumference(Baseline (preoperative, before spinal anesthesia) and early postoperative period (within 30 minutes after cesarean section))
- Incidence of hypotension after spinal anesthesia(Within the first 30 minutes after spinal anesthesia)
- Vasopressor requirement(Perioperative period)
研究者
Serkan TELLİ
Assistant Professor
Kutahya Health Sciences University