Comparison of the effects of clonidine and tranexamic acid on the amount of bleeding during tympanoplasty

Phase 3

Recruiting

• Conditions: Condition 1: Tympanoplasty. Condition 2: Hemorrhage.; Cellulitis of external ear, unspecified ear; Hemorrhage, not elsewhere classified; H60.10

• Registration Number: IRCT20230523058274N1
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 July 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Patients aged 18 to 60 are candidates for tympanoplasty

Exclusion Criteria

Treated with tricyclic antidepressants or monoamine oxidase inhibitors
Patients with heart, liver, kidney diseases and severe mental disorders
Patients with systolic blood pressure above 160 mmHg and diastolic blood pressure above 90 mmHg.
Heart rate less than 50 per minute

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bleeding. Timepoint: During tympanoplasty surgery. Method of measurement: A 4-point scoring system was evaluated, 0 = no bleeding, 1 = brief (suction rarely), 2 = heavy bleeding (frequent suction) and 3 = very heavy bleeding (conditions of surgical problem and continuous suction).;Hemodynamic variables. Timepoint: It was recorded every 10 minutes before and after pre-drug injection, after induction of anesthesia, after intubation, before surgery and then during surgery. Method of measurement: ???? ????????.