A clinical trial to study the effect of Single dose steroid on major hepatectomy
Phase 3
Not yet recruiting
- Conditions
- Other specified diseases of liver,
- Registration Number
- CTRI/2022/10/046832
- Lead Sponsor
- Muddada Vivekananda
- Brief Summary
This study is a randomised controlled trail evaluating the imapct of single dose Methylprednisolone on major hepatectomy in adults in 120 patients that will be conducted in single centre in India.The primary outcome is to compare post operative complications within 90 days after liver resection.The secondary outcome will be to compare Perioperative mortality,Levels of CRP,LFT and Length of Hospital stay.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Patients undergoing Major Hepatectomy.
Exclusion Criteria
1.Patients who deny consenting for study 2.Patients who are on steroids for other conditions 3.Patients undergoing recipient Hepatectomy 4.Patients undergoing Minor hepatectomy/Non anatomic liver resections.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare post operative complications Within 90days after Liver resection
- Secondary Outcome Measures
Name Time Method 1.peri-operative Mortality 2.Inflammatory marker - CRP at baseline and on POD 1,3 and 5 and during follow up visit
Trial Locations
- Locations (1)
Amrita Institute of medical sciences
🇮🇳Ernakulam, KERALA, India
Amrita Institute of medical sciences🇮🇳Ernakulam, KERALA, IndiaMuddada VivekanandaPrincipal investigator9845806688vivekananda70@gmail.com