The Effects of an Insulinotropic Protein-carbohydrate Beverage on L- Carnitine Absorption and Muscle Carnitine Uptake
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 7
- 主要终点
- Muscle carnitine uptake
研究概览
简要总结
The purpose of this study is to assess the effects of a protein-carbohydrate beverage on the absorption of an orally ingested bolus of L-carnitine, compared to flavoured water and carbohydrate-only controls, and to determine whether increasing plasma carnitine availability can impact upon insulin-stimulated muscle carnitine uptake.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Body mass index of 18-25 kg/cm2
排除标准
- •Unhealthy
- •Taking any medication that interferes with skeletal muscle metabolism
研究组 & 干预措施
CHO
500 ml of flavoured water containing 80 g carbohydrate
干预措施: Flavoured water + carbohydrate (Dietary Supplement)
CON
500 ml of flavoured water
干预措施: Flavoured water (Dietary Supplement)
CHO-PRO
500 ml of flavoured water containing 40 g carbohydrate and 40 g whey protein
干预措施: Flavoured water + carbohydrate + protein (Dietary Supplement)
结局指标
主要结局
Muscle carnitine uptake
时间窗: 180 minutes
Change in forearm carnitine uptake (measured using arterialised-venous - venous balance technique) in response to intervention.
次要结局
未报告次要终点