Protein Ingestion and Muscle Carnitine Uptake

Phase 1

Completed

• Conditions: Muscle, Skeletal

• Registration Number: NCT02535897
• Lead Sponsor: University of Nottingham

Brief Summary

The purpose of this study is to assess the effects of a protein-carbohydrate beverage on the absorption of an orally ingested bolus of L-carnitine, compared to flavoured water and carbohydrate-only controls, and to determine whether increasing plasma carnitine availability can impact upon insulin-stimulated muscle carnitine uptake.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07
• Primary Completion: 2014-02
• Study Completion: 2014-07
• Status Verified: 2015-08
• Study First Submitted: 2015-08-24
• Study First Submitted QC: 2015-08-28
• Last Update Submitted: 2015-08-28
• Study First Posted: 2015-08-31
• Last Update Posted: 2015-08-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 7

Inclusion Criteria

• Healthy
• Body mass index of 18-25 kg/cm2

Exclusion Criteria

• Unhealthy
• Smoker
• Taking any medication that interferes with skeletal muscle metabolism

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Muscle carnitine uptake	180 minutes	Change in forearm carnitine uptake (measured using arterialised-venous - venous balance technique) in response to intervention.