Protein Hydrolyzation and Glycemic Control

Not Applicable

Completed

• Conditions: Diabetes
• Interventions: Dietary Supplement: Protein hydrolyzation

• Registration Number: NCT01034618
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

The insulinotropic effects of protein hydrolysate/amino acid ingestion have been shown to regulate blood glucose homeostasis in both type 2 diabetes patients and normoglycemic controls. The objective of the study is to investigate the optimal dose of such an insulinotropic mixture.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-12
• Primary Completion: 2008-10
• Study Completion: 2009-04
• Status Verified: 2009-12
• Study First Submitted: 2009-12-16
• Study First Submitted QC: 2009-12-16
• Last Update Submitted: 2009-12-16
• Study First Posted: 2009-12-17
• Last Update Posted: 2009-12-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

• Male
• Age between 40 and 70 years
• Oral blood glucose lowering medication
• BMI < 35 kg/m2

Exclusion Criteria

• Exogenous insulin use
• Cardiac disease (any cardiac event in the last 5 years)
• Diabetic complications (microvascular complications, microalbuminuria: albumin:creatinine ratio >2,5)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Placebo	Protein hydrolyzation	-
Intact protein	Protein hydrolyzation	-
Protein hydrolysate	Protein hydrolyzation	-

Primary Outcome Measures

Name	Time	Method
Glucose and insulin homeostasis.

Secondary Outcome Measures

Name	Time	Method
Plasma amino acid profiles

Trial Locations

Locations (1)

Maastricht University Medical Center+; 🇳🇱 Maastricht, Limburg, Netherlands