Influence of Protein Hydrolysis on Dietary Protein Digestibility and Metabolism in Healthy Subjects
Not Applicable
Completed
- Conditions
- Healthy
- Registration Number
- NCT00873951
- Brief Summary
Hydrolysis of dietary protein may impact their gastrointestinal kinetics and further metabolism. The primary goal of this work was to measure the metabolic fate of intact or hydrolyzed protein using a protein of good nutritional quality, i.e., casein. A second aim of this study was to assess the true ileal digestibility of dietary protein using different methods including the hydrolyzed casein method and to measure its possible effect on endogenous intestinal N losses in humans.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 26
Inclusion Criteria
- healthy subjects
- BMI between 18 and 25
Exclusion Criteria
- allergy to dairy proteins
- positive serology to AgHbS, HCV or HIV
- pregnancy
- abusive drug or alcohol consumption.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Postprandial metabolic fate of dietary N 0h-1h-2h-3h-4h-5h-6h-7h-8h postprandial
- Secondary Outcome Measures
Name Time Method Differences in ileal digestibility determination according to the method used 8h postprandial
Trial Locations
- Locations (1)
Centre de recherche sur volontaires
🇫🇷Bobigny, France
Centre de recherche sur volontaires🇫🇷Bobigny, France