Investigation of the Detection Rate of Pathogenic Viruses in the Feces of Individuals With Non-gastrointestinal Infections
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- virus infection checklist
研究概览
简要总结
This project is a cross-sectional study. Investigators plan to search and collect 1600 publicly published fecal metagenomic and metatranscriptome data through the Pubmed database, by summarizing and analyzing them to construct an enterovirus database. 200 apparently healthy individuals are planned to be enrolled. At the time of enrollment, fecal specimens of participants will be collected, and their demographic characteristics, disease and medication history, gastrointestinal status, dietary habits, lifestyle habits, and mental health information will be recorded. Another 200 specimens will be collected from patients with parenteral virus infection. The demographic characteristics and pathogen test results of the parenteral virus infected patients will be reviewed and recorded. By virus metagenomic sequencing on fecal specimens, investigators will identify which viruses can be detected in the intestinal tract of apparently healthy people, and to explore whether parenteral infection viruses can be detected in feces.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age ranged from 18 to 75 years;
- •no obvious symptoms and signs of the disease;
- •not taking a drug for a long time;
- •good psychological condition ;
- •no unhealthy lifestyle;
- •willing to participate in the study, sign the informed consent, fill out the questionnaire and provide fecal samples.
排除标准
- •pregnant and lactating women;
- •suffering from certain diseases, such as cardiovascular disease, digestive system disease and nervous system disease.
结局指标
主要结局
virus infection checklist
时间窗: 2024.3-2025.12
Viral infections in the respiratory system, digestive system, urinary system, cardiovascular system, etc.
次要结局
- Self-rating depression scale SDS(2024.3-2025.12)
- general information of apparently healthy individuals by questionnaire(2024.3-2025.12)
- demographic characteristics case information of parenteral virus infected patients(2024.3-2025.12)
- Self-Rating Anxiety Scale SAS(2024.3-2025.12)
- Pittsburgh sleep quality index PSQI(2024.3-2025.12)
研究者
Yan He
Professor
Zhujiang Hospital