BioNTech

- Country
- 🇩🇪Germany
- Ownership
- Public
- Employees
- 6.1K
- Market Cap
- $20.7B
- Website
- http://www.biontech.de
- Introduction
BioNTech SE operates as immunotherapy company, which engages therapies for cancer and other serious diseases. Its product pipeline include BNT162b2, BNT161, BNT164, FixVac, iNeST, RiboMabs, CAR-T Cells, TCRs and Next-Gen CP Immunomodulators. The company was founded by Christopher Huber, Oezlem Tuereci, and Ugur Sahin on June 2, 2008 and is headquartered in Mainz, Germany.
Clinical Trials
107
Trial Phases
5 Phases
Drug Approvals
0
Drug Approvals
No drug approvals found
This company may not have drug approvals in our database
Clinical Trials
Distribution across different clinical trial phases (102 trials with phase data)• Click on a phase to view related trials
A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From Sperm
- Conditions
- Testicular Germ Cell TumorExtragonadal Germ Cell Tumor
- Interventions
- Biological: CLDN6 CAR-T
- First Posted Date
- 2025-04-23
- Last Posted Date
- 2025-07-02
- Lead Sponsor
- BioNTech SE
- Target Recruit Count
- 150
- Registration Number
- NCT06940804
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
- First Posted Date
- 2025-03-24
- Last Posted Date
- 2025-07-11
- Lead Sponsor
- BioNTech SE
- Target Recruit Count
- 594
- Registration Number
- NCT06892548
- Locations
- 🇺🇸
Precision NextGen Oncology and Research Center, Beverly Hills, California, United States
🇺🇸Virginia Cancer Specialists, Fairfax, Virginia, United States
Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy Following Chemoimmunotherapy
- First Posted Date
- 2025-02-24
- Last Posted Date
- 2025-07-08
- Lead Sponsor
- BioNTech SE
- Target Recruit Count
- 60
- Registration Number
- NCT06841055
- Locations
- 🇺🇸
Baptist Health Hardin, Elizabethtown, Kentucky, United States
🇺🇸NYU Langone - NYU Grossman School of Medicine, New York, New York, United States
🇺🇸Millennium Research and Clinical Development, LLC, Houston, Texas, United States
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
- Conditions
- Locally Advanced Breast CancerUnresectable Breast CarcinomaMetastatic Breast Cancer
- Interventions
- First Posted Date
- 2025-02-14
- Last Posted Date
- 2025-07-11
- Lead Sponsor
- BioNTech SE
- Target Recruit Count
- 380
- Registration Number
- NCT06827236
- Locations
- 🇨🇳
Huizhou First Hospital, Huizhou, China
🇨🇳Fudan University Shanghai Cancer, Shanghai, China
🇺🇸Hematology - Oncology Associates of the Treasure Coast, Port Saint Lucie, Florida, United States
A Study to Learn About How the Flu and COVID-19 Vaccines Act in Healthy People
- Conditions
- InfluenzaCOVID-19 (Coronavirus Disease 2019)
- Interventions
- Biological: Investigational COVID-19 VaccineCombination Product: Investigational Influenza and COVID-19 Combination VaccineBiological: Licensed COVID-19 VaccineBiological: Licensed Influenza Vaccine 3Biological: Licensed Influenza Vaccine 1Biological: Licensed Influenza Vaccine 2Biological: Investigational Influenza Vaccine
- First Posted Date
- 2025-02-11
- Last Posted Date
- 2025-06-24
- Lead Sponsor
- BioNTech SE
- Target Recruit Count
- 2645
- Registration Number
- NCT06821061
- Locations
- 🇺🇸
Upstate Global Health Institute, East Syracuse, New York, United States
🇺🇸University of Rochester Medical Center, Rochester, New York, United States
🇺🇸AMR Clinical, Knoxville, Tennessee, United States
- Prev
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News
Sartorius Stedim Biotech Partners with Sensible Biotechnologies to Scale Cell-Based mRNA Manufacturing Platform
Sartorius Stedim Biotech and Sensible Biotechnologies have signed a Memorandum of Understanding to advance the industrialization of Sensible's first-in-class cell-based mRNA manufacturing platform.
Everest Medicines Advances AI-Powered mRNA Platform with Cancer Vaccine Breakthroughs
Everest Medicines unveiled major breakthroughs in its proprietary AI-powered mRNA platform during its 2025 R&D Day, showcasing a fully integrated system spanning antigen design to manufacturing.
NCT/UCC Dresden Launches Phase 2 Trial of Personalized mRNA Vaccine for Pancreatic Cancer
NCT/UCC Dresden becomes the only site in Saxony to offer patients access to BioNTech and Genentech's personalized mRNA vaccine Autogene Cevumeran for pancreatic cancer treatment.
BioNTech Shuts Down Maryland Cell Therapy Manufacturing Following CAR-T Trial Failure
BioNTech will lay off 63 employees and wind down cell therapy manufacturing at its Gaithersburg, Maryland facility by the end of 2025 following disappointing Phase 1 trial results.
BioNTech to Acquire CureVac for $1.25 Billion to Strengthen mRNA Cancer Immunotherapy Pipeline
BioNTech announced a $1.25 billion all-stock acquisition of CureVac through a public exchange offer, offering $5.46 per CureVac share representing a 55% premium to strengthen its mRNA-based cancer immunotherapy capabilities.
RFK Jr. Replaces Entire CDC Vaccine Advisory Committee with Eight New Members
Health Secretary Robert F. Kennedy Jr. has replaced all 17 members of the CDC's Advisory Committee on Immunization Practices with eight new appointees, significantly downsizing the committee.
Bristol Myers Squibb Partners with BioNTech in $11.1 Billion Deal for Dual-Target Cancer Immunotherapy
Bristol Myers Squibb will pay BioNTech $1.5 billion upfront plus $2 billion in anniversary payments through 2028 for a 50% partnership in BNT327, a bispecific antibody targeting both PD-L1 and VEGF proteins.
FDA Expands Warning for mRNA COVID-19 Vaccines Due to Heart Side Effect Risk in Young Males
The FDA has ordered Pfizer and Moderna to expand warning labels on their COVID-19 vaccines regarding myocarditis and pericarditis risk, particularly in males aged 16-25, with an incidence rate of 38 cases per million doses.
Breakthrough in Targeted Drug Delivery: Novel Bacteriophage-Loaded Wound Dressings Show Promise for Chronic Infections
Professor Maike Windbergs and her team at Goethe University Frankfurt have developed innovative wound dressings using electrospinning technology that gradually release bacteriophages to combat resistant bacteria in chronic wounds.
Ethris and Lonza Partner to Develop Room-Temperature Stable mRNA Respiratory Vaccines
Ethris and Lonza have formed a strategic partnership to develop spray-dried mRNA vaccines for respiratory diseases that remain stable at room temperature, eliminating cold chain requirements.