To study the importance of causation (trauma) rubric in traumatic osteoarthritis of knee.
- Conditions
- Health Condition 1: M172- Bilateral post-traumatic osteoarthritis of knee
- Registration Number
- CTRI/2023/06/054561
- Lead Sponsor
- CLINICAL RESEARCH UNIT FOR HOMOEOPATHY. RANCHI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 75
1. Age: 50-70 years
2. Both sexes
3. Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR) clinical/radiographic classification criteria, 30 (sensitivity 91%; specificity 86%) - history of trauma over knee, knee pain, stiffness less than 30 min, and crepitus on knee motion, osteophytes on a knee x-ray
4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis, provided the medications are stopped at least 2 weeks prior to study entry entirely
5. Literate patients; can able to read Hindi or English
6. Providing written informed consent
1. Severe degeneration of the knee joint with marked joint narrowing, varus or valgus deformity of the knee ( >12°), evidenced by imaging or other evidence and requiring surgical intervention
2.Non-ambulant patients
3. Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, hyperuricaemia and/or gout, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs)
4. Intra-articular injections within 2 weeks before study entry
5. Transplanted knees
6. Recent significant knee surgery within the last 6 months
7. Patients who are too sick for consultation
8. Unwilling to take part and not giving consent to join the study
9. Unable to read the patient information sheet
10 Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting the quality of life
11. Pregnancy and lactation
12. Substance abuse and or dependence
13. Self-reported immune-compromised state, and
14. Undergoing homoeopathic treatment for any chronic disease within the last 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate group differences in Knee Injury and Osteoarthritis Outcome Score (KOOS) between the two groups over 3 months of intervention;Timepoint: Monthly Follow-up up to 3 months
- Secondary Outcome Measures
Name Time Method To evaluate group differences in quality of life measured in terms of EQ-5D-5L measures between the two groups over 3 months of intervention.Timepoint: Monthly Follow-up up to 3 months