MedPath

Implementation of a Social and Mental Health Support to Promote Recovery in Five Mental Health Facilities in Paris Area

Not Applicable
Not yet recruiting
Conditions
Severe Mental Disorder
Interventions
Behavioral: Patient group/Passvers
Registration Number
NCT05274126
Lead Sponsor
Versailles Hospital
Brief Summary

Prospective longitudinal uncontrolled multicenter study, with cohort follow-up, focusing on patients, professionals, relatives and structures evolution during the implementation of recovery based intervention.

Detailed Description

This is a hybrid efficacy-implementation Type I recovery based interventional study based on a multicenter follow-up of a cohort of 300 patients with severe and persistent mental disorders (60 patients per center). The evolution of concepts and means of evaluation now allow a precise description of the mechanisms of recovery in all the diversity of its expression among patients, their entourages and the psychiatric facilities.

In the present study, the investigators aim to characterize simultaneously the patients' trajectories and the evolution of the care facilities and their professionals with respect to the principles of recovery. This double exploration should allow to build theoretical and practical references for the extension of this approach to other centers in France.

The study considers a dual timeline for data collection:

* The timeline associated with patients defined by the inclusion of each patient and extending to 24 months after, punctuated by an assessment at 12 months;

* The timeline of the inclusion centers and professionals involved in the rehabilitation projects defined by the beginning of the study and extending beyond the end of inclusion of the last patient, punctuated by annual intermediate evaluations of the means allocated by the structure and the positioning of the personnel in terms of recovery.

The intervention consists in a follow-up of the patients and their relatives by a psychiatric nurse and a social worker during 12 months. Both professionals, trained to rehabilitation and recovery principles, will focus on the patient's needs and goals in order to improve the outcome, quality-of-life and clinical status.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
300
Inclusion Criteria
  • Presence of a severe and persistent mental disorder among the following ICD10 compliant diagnostic categories:

    • Schizophrenia spectrum disorder (F2x)
    • Recurrent or persistent mood disorders (F30.x, F31.x, F33.x, F34.x, F38.x)
    • Psychological developmental disorders including autism spectrum disorders (F8x) and childhood and adolescent onset disorders (F9x)
  • Presence of an indication for inclusion in the rehabilitation project identified by the treating psychiatrist and endorsed in the inclusion session by the PASSVers staff.

  • Written consent from the patient or his/her legal representative to participate in the study.

Exclusion Criteria
  • Presence of an not stabilized or progressive organic neurological pathology, neurodegenerative disease

  • Psychological or behavioral disorders mainly related to addictions with substances

  • Psychiatric disorders secondary to an organic pathology that is not stabilized or that is evolving

  • The following psychiatric situations are reasons for non-inclusion in the absence of an argued and collegial reassessment (the reason being that, although PASSVers2 must be considered as a first intention proposal in many situations meeting the inclusion criteria, it cannot intervene or be thought of as a "solution" to certain complex situations):

    • Psychiatric disorders caused by pregnancy or immediate postpartum
    • Severe borderline personality disorder
    • Current suicidal crisis
    • Extreme fragility of the patient with respect to changes that may be induced by the project, associated with a high risk of self or hetero-aggression.
    • Patient under justice constraint
  • Foreseeable departure from the geographic area, not allowing for certainty of further evaluation

  • Refusal of the patient to be followed by a social-health team (i.e. refusal of care or refusal of a dialogue on social aspects and projects).

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Patient group (single group)Patient group/Passvers300 Patients involved in the recovery process.
Primary Outcome Measures
NameTimeMethod
Patient self rating of recovery support by caregivers T121 year

5-item short version of INSPIRE measure (Brief INSPIRE), range from 5 to 25, 25 corresponds to maximal support

Patient self rating of recovery support by caregivers and structure T121 year

Recovery Self-Assessment (RSA-R), range from 32 to 160, higher values correspond to more perceived help

Patient self rating of recovery support by caregivers T0baseline

5-item short version of INSPIRE measure (Brief INSPIRE), range from 5 to 25, 25 corresponds to maximal support

Patient self rating of recovery support by caregivers and structure T0baseline

Recovery Self-Assessment (RSA-R), range from 32 to 160, higher values correspond to more perceived help

Patient functioning T0baseline

Personal and Social Performance scale (PSP), range 0-100, 100 corresponds to better functioning

Psychotic symptoms T0baseline

Positive and negative syndrome scale (PANSS), range 30-210, higher values correspond to higher symptoms levels

Psychotic symptoms T121 year

Positive and negative syndrome scale (PANSS), range 30-210, higher values correspond to higher symptoms levels

Depression T121 year

Psychiatric symptoms scales rated by the clinicians (CDSS), range 0-27, higher values correspond to higher depressive symptoms

Clinical outcome T0: Clinically significant eventsbaseline

Record of occurrences (boolean) and dates of any clinical event (hospitalizations, self-harming behavior) occurring during the course of the illness

Patient self rating of recovery T242 years

Questionnaire about the process of recovery (QPR), range from 22 to 110, higher values correspond to better recovery

Patient functioning T121 year

Personal and Social Performance scale (PSP), range 0-100, 100 corresponds to better functioning

Patient self rating of quality of life T121 year

Shortened quality of life questionnaire (SQoL-18), range 18-90, higher values correspond to better quality of life

Patient functioning T242 years

Personal and Social Performance scale (PSP), range 0-100, 100 corresponds to better functioning

Patient self rating of quality of life T0baseline

Shortened quality of life questionnaire (SQoL-18), range 18-90, higher values correspond to better quality of life

Clinical outcome T12: Clinically significant events1 year

Record of occurrences (boolean) and dates of any clinical event (hospitalizations, self-harming behavior) occurring during the course of the illness

Patient self rating of recovery T121 year

Questionnaire about the process of recovery (QPR), range from 22 to 110, higher values correspond to better recovery

Patient self rating of quality of life T242 years

Shortened quality of life questionnaire (SQoL-18), range 18-90, higher values correspond to better quality of life

Depression T0baseline

Psychiatric symptoms scales rated by the clinicians (CDSS), range 0-27, higher values correspond to higher depressive symptoms

Patient self rating of recovery T0baseline

Questionnaire about the process of recovery (QPR), range from 22 to 110, higher values correspond to better recovery

Secondary Outcome Measures
NameTimeMethod
Perceived needs T0baseline

Perceived needs scale (ELADEB), Composite measure of perceived difficulty in meeting needs and needs of help

Sleep T0baseline

Patient self rating of sleep (1 item Pittsburgh sleep quality index PSQI), range 1-4, lower values correspond to better sleep quality

Professional's Recovery opinions on patients T121 year

Practitioners' Beliefs, Goals and Practices in Psychiatric Rehabilitation (PBGP), range 26-104, higher values correspond to better views on patients recovery

Stigmatization T0baseline

Internalized stigma of mental illness: self-stigma (ISMI), range 29-116, higher values correspond to worse stigmatization perception

Perceived needs T121 year

Perceived needs scale (ELADEB), Composite measure of perceived difficulty in meeting needs and needs of help

Cognitive disability T0baseline

Cognitive processes involved in disability in schizophrenia scale (CPSD), range 0-78, higher values correspond to better cognitive functioning

Professional's Recovery knowledge on patients T121 year

Recovery knowledge inventory (RKI), range 20-100, higher values correspond to better knowledge on recovery processes

Professional's Recovery opinions on patients T0baseline

Practitioners' Beliefs, Goals and Practices in Psychiatric Rehabilitation (PBGP), range 26-104, higher values correspond to better views on patients recovery

Goal achievement T121 year

Goal achievement scale (GAS), range -2 to +2, higher values correspond to better achievement of one specific goal

Metacognitive strategies T0baseline

Versailles Metacognitive Strategies Evaluation Questionnaire (V-MSEQ), range 25-175, higher values correspond to better metacognitive strategies

Entourage assessment of structure recovery orientation T0baseline

Recovery Self-Assessment Significant other version (RSA-R entourage), range 40-200, higher values correspond to better recovery orientation

Stigmatization T121 year

Internalized stigma of mental illness: self-stigma (ISMI), range 29-116, higher values correspond to worse stigmatization perception

Sleep T121 year

Patient self rating of sleep (1 item Pittsburgh sleep quality index PSQI), range 1-4, lower values correspond to better sleep quality

Medication adherence T121 year

Medication Adherence Rating Scale (MARS), range 5-25, lower values correspond to better adherence to treatment

Illness severity T0baseline

Clinical Global Impressions Scale (CGI-S), range 1-7, higher values correspond to more severe illness

Illness severity T121 year

Clinical Global Impressions Scale (CGI-S), range 1-7, higher values correspond to more severe illness

Entourage assessment of structure recovery orientation T121 year

Recovery Self-Assessment Significant other version (RSA-R entourage), range 40-200, higher values correspond to better recovery orientation

Professional's Recovery knowledge on patients T0baseline

Recovery knowledge inventory (RKI), range 20-100, higher values correspond to better knowledge on recovery processes

Medication adherence T0baseline

Medication Adherence Rating Scale (MARS), range 5-25, lower values correspond to better adherence to treatment

Cognitive disability T121 year

Cognitive processes involved in disability in schizophrenia scale (CPSD), range 0-78, higher values correspond to better cognitive functioning

Trial Locations

Locations (5)

Centre Hospitalier d'Argenteuil, secteurs 95G05, 95G06, 95G13,

🇫🇷

Argenteuil, France

Hôpital Sainte Anne - GHU Paris Psychiatrie & Neurosciences, secteur G75015

🇫🇷

Paris, France

Etablissement de Santé Mentale de Rueil-Malmaison, Groupe MGEN, secteur 92G13, CMP de Rueil-Malmaison

🇫🇷

Rueil-Malmaison, France

Centre Hospitalier de Versailles, secteur 78G17, Centre Bleuler, Versailles

🇫🇷

Versailles, France

Centre Hospitalier de Plaisir, secteur 78G16, CMP de Rambouillet

🇫🇷

Rambouillet, France

© Copyright 2025. All Rights Reserved by MedPath