Pulmonaryhypertension in Copd at Different Levels of Smoking

Not yet recruiting

• Conditions: Pulmonary Hypertension

• Registration Number: NCT06031311
• Lead Sponsor: Assiut University

Brief Summary

To identify Predictors of pulmonary hypertension in COPD patients and its relation to different levels of smoking

Detailed Description

COPD is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, expectoration and/or exacerbations) due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction.It is also the most common cause of deaths in patients with chronic respiratory disease, the fatality rate in USA is 0.41%.Pulmonary Hypertension is the most common serious complication in COPD patients ; which occurs in up to 30% of patients and increases the mortality rate.Smoking is the leading cause of chronic obstructive pulmonary disease (COPD) Smoking is also a trigger for COPD flare-ups.Smoking damages the air sacs, airways, and the lining of your lungs. Injured lungs have trouble moving enough air in and out, so it's hard to breathe

Study Timeline

• Status Verified: 2023-09
• Study First Submitted: 2023-09-02
• Study First Submitted QC: 2023-09-02
• Study First Posted: 2023-09-11
• Last Update Submitted: 2023-09-13
• Last Update Posted: 2023-09-14
• Study Start: 2023-10-01
• Primary Completion: 2024-10-01
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

• 1.All patients admitted to chest department or presented to our outpatient clinic with clinical and functional diagnosis of COPD among both sexes will be included 2.Age >18 years Old

Exclusion Criteria

• 1.Patients under 18 years old. 2.pregnant patients. 3.patients with history hypertension or valvular diseases 4.Cardiomyopathic patient 5.Patients with concomitant obstructive sleep apnea 6.Patients with collagen vascular disease 7.Patients with thrombo-embolic disease 8. Patients with any chronic chest disease other than COPD

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Predictors of pulmonary hypertension in COPD patients	1 year	Predict pulmonary hypertension in COPD patients

Secondary Outcome Measures

Name	Time	Method
Relationship between different levels of smoking and predictors of degree of pulmonary hypertension	1 year	Levels of smoking (mild.moderate.sever.non smoker) and it's relation to pulmonary hypertension in COPD patients