Clinical Characteristics and Predictors of Pulmonary Hypertension in COPD at Different Levels of Smoking
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 138
- 主要终点
- Predictors of pulmonary hypertension in COPD patients
研究概览
简要总结
To identify Predictors of pulmonary hypertension in COPD patients and its relation to different levels of smoking
详细描述
COPD is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, expectoration and/or exacerbations) due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction.It is also the most common cause of deaths in patients with chronic respiratory disease, the fatality rate in USA is 0.41%.Pulmonary Hypertension is the most common serious complication in COPD patients ; which occurs in up to 30% of patients and increases the mortality rate.Smoking is the leading cause of chronic obstructive pulmonary disease (COPD) Smoking is also a trigger for COPD flare-ups.Smoking damages the air sacs, airways, and the lining of your lungs. Injured lungs have trouble moving enough air in and out, so it's hard to breathe
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1.All patients admitted to chest department or presented to our outpatient clinic with clinical and functional diagnosis of COPD among both sexes will be included 2.Age >18 years Old
排除标准
- •1.Patients under 18 years old. 2.pregnant patients. 3.patients with history hypertension or valvular diseases 4.Cardiomyopathic patient 5.Patients with concomitant obstructive sleep apnea 6.Patients with collagen vascular disease 7.Patients with thrombo-embolic disease
- •Patients with any chronic chest disease other than COPD
结局指标
主要结局
Predictors of pulmonary hypertension in COPD patients
时间窗: 1 year
Predict pulmonary hypertension in COPD patients
次要结局
- Relationship between different levels of smoking and predictors of degree of pulmonary hypertension(1 year)
研究者
Shrouk Mohamed Salah Mosleh
Resident doctor
Assiut University