Radiotherapy to major salivary glands in patients with parkinsonism and severe drooling.
Completed
- Conditions
- DroolingSialorrhoea10028037
- Registration Number
- NL-OMON34663
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 45
Inclusion Criteria
Inclusion criteria are:
1. Clinical symptoms of parkinsonism
2. A diagnosis of severe sialorrhoea (score 3 or 4 on item 6 of the Activities of Daily Living (ADL) section of the Unified Parkinson*s Disease Rating Scale (UPDRS))
3. Written informed consent obtained from the patient
4. All patients must be older than 50 years of age
Exclusion Criteria
Exclusion criteria are:
1. Concurrent participation in another investigational study.
2. The use of drugs, like anticholinergic drugs, that interfere with saliva secretion.
3. Previous surgical procedures in the oral or nasal cavity interfering with saliva production.
4. A history of (pre)malignancy in the radiation treatment portal.
5. Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method