Effect of Low-Level Laser on Crevicular Interleukin-1β Concentration in Patients with Periodontal Disease: a Relation to Periodontal Inflammaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Gingival index
研究概览
简要总结
This study is done to compare between young age and old age patients with periodontitis (inflammaging) and the effect of diode laser as adjunctive to scaling and debridement
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or Female
- •Aged below 40 or above
- •Provide informed consent and willingness to cooperate with study protocol.
- •Periodontitis stage II patients:
- •CAL from 3-4 mm.
- •Radiographic bone loss (15% to 33%).
- •No tooth loss due to periodontitis.
- •Maximum probing depth ≤ 5 mm, mostly horizontal bone loss
排除标准
- •Patients with heavy smoking habits
- •History of antibiotics in the previous three months.
- •Pregnant or lactating female.
- •Treatment with any systemic drug.
- •History of systemic disease.
- •Patients who received periodontal treatment in the last 6 months
研究组 & 干预措施
Conventional scaling and debridement in young aged patients
scaling and debridement
干预措施: conventional scaling and debridement (Procedure)
Conventional scaling and debridement of old aged patients
干预措施: conventional scaling and debridement (Procedure)
diode laser as adjunctive to conventional scaling and debridement for old age patients
干预措施: diode laser as adjunctive to conventional scaling and debridement (Radiation)
diode laser as adjunctive to conventional scaling and debridement for young age patients
干预措施: diode laser as adjunctive to conventional scaling and debridement (Radiation)
结局指标
主要结局
Gingival index
时间窗: first visit, second follow up after 1 month and final follow up after 6 months
Clinical attachment loss
时间窗: first visit, second follow up after 1 month and final follow up after 6 months
Interleukin 1 beta
时间窗: first visit, second follow up after 1 month and final follow up after 6 months
collected and analyzed by ELISA from Gingival crevicular fluid and blood serum
次要结局
未报告次要终点
研究者
Asmaa EssamEldin Ahmed
Teaching assistant
Misr University for Science and Technology