Sevoflurane/fentanyl anesthesia guided by Nociceptive-Level index during abdominal surgery in ASA 1-3 patients – a randomized controlled trial on the effect of NOL-guidance on postoperative pain scores
Recruiting
- Conditions
- Surgical patients
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
1.Age: 18 years and older;
2.ASA I-II-III
3.Elective open abdominal surgery or robot/laparoscopic assisted abdominal surgery.
Exclusion Criteria
1.Unable to give written informed consent;
2.Use of epidural analgesia or local anesthesia (eg. transversus abdominal plain block, TAP block)
3.Non-elective surgery
4.Pregnancy/lactation.
5.BMI > 35 kg/m2;
6.Uncontrolled preoperative hypo- or hypertension (Mean arterial pressure < 60 mmHg or systolic blood pressure > 160 mmHg)
7.Preoperative Heart rate < 45/min or > 90/min;
8.Central nervous system disorder (neurologic/head trauma/uncontrolled epileptic seizures);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative pain score
- Secondary Outcome Measures
Name Time Method (!) Postoperative opioid consumption as measured in the first 90 min of PACU stay<br>(2) Fentanyl use during anesthesia;<br>(3) Sevoflurane consumption during anesthesia;<br>(4) Inadequate hemodynamic events, see Table 1;<br>(5) Time between reversal of neuromuscular block and extubation/eyes open;<br>(6) Occurrence of awareness;<br>(7) Anesthesia and surgery times/PACU stay time.<br>