Sevoflurane/fentanyl anesthesia guided by Nociceptive-Level index during abdominal surgery in ASA 1-3 patients * a randomized controlled trial on the effect of NOL-guidance on postoperative pain scores

Completed

• Conditions: perioperatieve patienten; anesthesia; pain

• Registration Number: NL-OMON48484
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-04-03
• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

1. Age: 18 years and older;
2. ASA I-II-III
3. Elective surgery

Exclusion Criteria

1. Unable to give written informed consent;
2. Use of epidural analgesia or local anesthesia (eg. transversus abdominal plain block, TAP block)
3. Non-elective surgery
4. Pregnancy/lactation.
6. Uncontrolled preoperative hypo- or hypertension (Mean arterial pressure < 60 mmHg or systolic blood pressure > 160 mmHg)
7.Preoperative Heart rate < 45/min or > 90/min;
8. Central nervous system disorder (neurologic/head trauma/uncontrolled epileptische aanvallen);

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Postoperartive pain</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Opioid and propofol consumption in total dose and dose/min; and<br /><br>Incidence (number of episodes) of inadequate anesthesia (as derived from heart<br /><br>rate, blood pressure, BIS values)</p><br>