Een studie naar farmacokinetiek en reproduceerbaarheid van 18Fluor -gelabelde choline in patienten met prostaat kanker.
- Conditions
- KeywordsEnglish: pharmacokinetics, repeatability, PET, choline, prostate cancer, kinetic model, standardised uptake value (SUV), region of interst (ROI), volume of interest (VOI).Dutch: farmacokinetiek, reproduceerbaarheid, PET, choline, prostaat kanker, kinetiek model, SUV, ROI, VOI.
- Registration Number
- NL-OMON26086
- Lead Sponsor
- VU University Medical Center, Amsterdam , The Netherlands.
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Part A:
1. Histologically proven prostate cancer, with lymphatic and/or haematogeneous metastases;
Exclusion Criteria
1. Claustrophobia (part A and B);
2. Multiple malignancies (part A and B);
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Part A: <br /><br>A pharmacokinetic model for [18F]FCH.<br><br /><br /><br>Part B: <br /><br>Test-retest variability of the simplified method of choice (part A) implemented in WB [18F]FCH PET-CT.
- Secondary Outcome Measures
Name Time Method Part A: Selection of an appropriate simplified quantitative method for use of [18F]FCH in clinical practice.