A cross sectional study to investigate the relationship between hormonal changes occurring post menopause and dental caries: a biomarker perspective
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 190
- 试验地点
- 1
- 主要终点
- A positive correlation between dental caries and pH level, salivary flow, salivary calcium, estradiol level and Vitamin D level in serum
研究概览
简要总结
A cross sectional study to investigate the relationship between hormonal changes occurring post menopause and dental caries: A biomarker perspective.
The aim is to evaluate the relationship between hormonal changes occurring post menopause and dental caries using biomarkers.
To determine if there is any correlation between salivary flow, salivary pH, hormonal fluctuations and micronutrient level to Dental Caries.
To evaluate and compare the flow and pH of saliva in Premenopausal and Post menopausal women.
To evaluate and compare the salivary Calcium of Premenopausal and post menopausal women.
To evaluate and compare the Estrogen (Estradiol) and Vitamin D level in serum of Premenopausal and post menopausal women.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- Female
入选标准
- •Premenopausal healthy women in the age group of 35-50years with no caries and having regular menstrual cycles.
排除标准
- •Women with any chronic diseases such as diabetes, chronic liver/renal diseases.
- •Women with any habits such as cigarette smoking, drinking alcohol Individuals on hormone replacement therapy Individual using any medicine on a regular basis that affects the salivary flow.
- •Pregnant women.
结局指标
主要结局
A positive correlation between dental caries and pH level, salivary flow, salivary calcium, estradiol level and Vitamin D level in serum
时间窗: checked within a day
次要结局
- To determine if there is any correlation between salivary flow, salivary pH, hormonal fluctuations & micronutrient level to Dental Caries.(To evaluate & compare the flow & pH of saliva in Premenopausal & Post menopausal women.)
研究者
Dr Abhipsha Lahiri
Siddhpur Dental College and Hospital