A Prospective Observational Cohort Study in Chinese Patients With Primary Intracerebral Hemorrhage
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 856
- 试验地点
- 1
- 主要终点
- proportion of patients with a 3-month modified Rankin Scale (mRS) score≤ 3
研究概览
简要总结
The investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese hospitalised adult patients with intracerebral hemorrhage.
详细描述
Intracerebral hemorrhage (ICH) remains a devastating disease with high mortality, yet few therapeutic managements have been proved effective. Large quantities of work needs to be done to fully delineate the prevalence and prognosis of ICH. Hence, the investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective, treatments and prognosis of Chinese hospitalised adult patients with ICH.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized patients over 18 years old of primary intracerebral hemorrhage.
排除标准
- •patients of secondary intracerebral hemorrhage，such as hemorrhagic transformation of ischemic stroke, aneurysmal, cavernomas, arterio- venous malformations, central venous thrombosis, trauma-related, or tumor.
- •isolated intraventricular hemorrhage or subarachnoid hemorrhage pregnant patients；
- •surgical evacuation of hematoma；
- •unavailability to get complete blood cell samples and presenting contraindications or refusal to MRI
- •patients cannot be followed up for any reasons.
- •patients death in 24 hours
- •pregnant patients
结局指标
主要结局
proportion of patients with a 3-month modified Rankin Scale (mRS) score≤ 3
时间窗: 2-3years
mRS 0-6, higher indicate worse outcome
次要结局
- Relative peripheral hematoma edema(rPHE)(2-3years)
- National institute of health stroke scale（NIHSS score）(2-3years)
- Absolute peripheral hematoma edema(PHE) growth(2-3years)