A Prospective Observational Cohort Study in Chinese Patients With Primary Intracerebral Hemorrhage
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Intracerebral Hemorrhage
- Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Enrollment
- 856
- Locations
- 1
- Primary Endpoint
- proportion of patients with a 3-month modified Rankin Scale (mRS) score≤ 3
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
The investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese hospitalised adult patients with intracerebral hemorrhage.
Detailed Description
Intracerebral hemorrhage (ICH) remains a devastating disease with high mortality, yet few therapeutic managements have been proved effective. Large quantities of work needs to be done to fully delineate the prevalence and prognosis of ICH. Hence, the investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective, treatments and prognosis of Chinese hospitalised adult patients with ICH.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Hospitalized patients over 18 years old of primary intracerebral hemorrhage.
Exclusion Criteria
- •patients of secondary intracerebral hemorrhage，such as hemorrhagic transformation of ischemic stroke, aneurysmal, cavernomas, arterio- venous malformations, central venous thrombosis, trauma-related, or tumor.
- •isolated intraventricular hemorrhage or subarachnoid hemorrhage pregnant patients；
- •surgical evacuation of hematoma；
- •unavailability to get complete blood cell samples and presenting contraindications or refusal to MRI
- •patients cannot be followed up for any reasons.
- •patients death in 24 hours
- •pregnant patients
Outcomes
Primary Outcomes
proportion of patients with a 3-month modified Rankin Scale (mRS) score≤ 3
Time Frame: 2-3years
mRS 0-6, higher indicate worse outcome
Secondary Outcomes
- Relative peripheral hematoma edema(rPHE)(2-3years)
- National institute of health stroke scale（NIHSS score）(2-3years)
- Absolute peripheral hematoma edema(PHE) growth(2-3years)