The Effect of Methylphenidate on Decision-making Ability of ADHD Adults

Shalvata Mental Health Center1 site in 1 country58 target enrollmentJanuary 2008

ConditionsAttention Deficit Hyperactivity Disorder

Interventionsmethylphenidate sweetener pill

Drugsmethylphenidate

Overview

Phase: Phase 1
Intervention: methylphenidate
Conditions: Attention Deficit Hyperactivity Disorder
Sponsor: Shalvata Mental Health Center
Enrollment: 58
Locations: 1
Primary Endpoint: score in decision-making task 1
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of the study is to assess the effect of Methylphenidate on cognitive performance and decision-making ability of ADHD adults, and to compare this effect to the effect on healthy control adults.

Detailed Description

Two matched groups of adults - with and without ADHD diagnosis - will perform a battery of computerized tasks assessing sustained attention,working-memory,non-verbal IQ,and decision-making ability. In each group,half of the participants will perform the tasks after receiving a capsule containing methylphenidate (MPH), and the other half will perform the tasks after receiving placebo. Task performance measures will then be compared in order to assess the effect of MPH on these domains.

Registry

clinicaltrials.gov

Start Date

January 2008

End Date

December 2009

Last Updated

16 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Shalvata Mental Health Center

Eligibility Criteria

Inclusion Criteria

•adults in the age of 21-50

Exclusion Criteria

•pregnant or nursing women.
•people who suffer from a psychiatric disorder other than ADHD which could account for their inattention symptoms better than ADHD.
•people who lack judgment or are unable to communicate with the experimenters.
•people who are incapable of performing the computerized tasks due to sensory or motor disabilities.