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Clinical Observation of Ziyinliangxue Decoction Combined with Moxibustion in Treating Chronic Glomerulonephritis with Deficiency of Qi and Yi

Phase 1
Conditions
Chronic glomerulonephritis
Registration Number
ITMCTR2000003646
Lead Sponsor
Shanghai Traditional Chinese Medicine Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Meet the diagnostic criteria for chronic nephritis and the TCM criteria for Qi and Yin deficiency and blood stasis syndrome;
2. The 24-hour urine protein quantitative is 0.2g/24h-3.0g/24h;
3. Kidney function is within the normal range;
4. Aged 18-80 years old;
5. Hypertension, severe infections, water, electrolyte and acid-base balance disorders are effectively controlled, and blood potassium is within the normal range;
6. Accept the observation of this clinical trial voluntarily, have good compliance, and sign the informed consent.

Exclusion Criteria

1. Patients with unilateral or bilateral renal artery stenosis;
2. Patients with poor blood pressure control, SBP>160mmHg, or DBP>100mmHg;
3. Malignant tumor disease, hematological disease, neuropsychiatric disease or complicated disease (such as diabetes, hypertension) poorly controlled;
4. Pregnant or lactating women;
5. People with allergies or known allergies to test drug components;
6. Patients who participated in other clinical trials within the past 1 month;
7. The 24-hour urine protein quantitative is less than 0.2g/24h or greater than 3g/24h.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
rine routine;T cell subsets;Immunoglobulin;Urine Albumin/Urine Creatinine;Complement C3;24-hour urine protein quantification;
Secondary Outcome Measures
NameTimeMethod
Serum uric acid;Blood creatinine;Serum urea nitrogen;
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