Efficacy of Moraceae with chlorhexidine mouthwash on the microbial flora of critically ill intubated patients
Phase 2
Completed
- Conditions
- Ventilator-associated pneumonia is a common bacterial nosocomial infection in the intensive care units. Critically ill patients undergoing tracheal intubation are at high risk for pneumonia due to oraVentilator associated pneumonia, mouthwash, chlorhexidine, Moraceae
- Registration Number
- TCTR20190530003
- Lead Sponsor
- Faculty of Mecicine, Prince of Songkla University
- Brief Summary
Moraceae with CHX mouthwash had the same effectiveness as CHX alone on bacterial flora but exhibited less intolerable side effects than CHX alone.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1. Adults (age more than 18 years)
2. Admitted in the medical intensive care unit within 24 hours
3. Having a tracheal tube and expect to on mechanical ventilation at least 48 hours
4. No contraindication for Moraceae or chlorhexidine mouthwash
Exclusion Criteria
1. Pregnancy
2. Sensitivity of anaphylaxis to herbal preparation and chlorhexidine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oral microbial flora day 1 and day 4 colony forming unit
- Secondary Outcome Measures
Name Time Method Oral health day 1-7 modified Beck oral assessment score ,Ventilator associated pneumonia In admission period No of patients ,Adverse events In admission period No of adverse events