Bowel Colonization With Multi-drug Resistant Bacterial Species in Hospitalized Patients With acute-on Chronic Liver Failure (ACLF), and Its Relationship With Extra-intestinal Infectious Events and Short-term Outcomes

Institute of Liver and Biliary Sciences0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

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•1. Patients with Acute on Chronic Liver Failure admitted to the ward/High Dependency Unit/Intensive Care Unit.

•1.Patients on immunosuppressant medications or on daily steroids (excluding inhaled steroids) or >2 weeks.
•2.Patients with additional primary or acquired immunosuppressive states like hypogammaglobinemia, post-splenectomy, human immunodeficiency virus (HIV) infection etc.
•3.Neutropenia defined as absolute neutrophil count or total white blood cell count (WBC) <500/mm3
•4.Patients with extra-hepatic malignancy or on cytotoxic chemotherapy.
•5.Patients with ileus, bowel hypomotility, severe constipation requiring laxatives/purgatives or enemas to evacuate.
•6.Patients with fresh or altered blood in stools.
•7.Patients with anatomical predisposition to infection/ bacterial seeing like prosthesis or foreign body. Patients with exfoliative skin conditions, significant mucosal ulcerations, or skin ulcers. Patients who have received > 2 weeks of antibiotics before current admission.
•8.Pregnant patients.

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