Evaluation of the Potential Impact of Probiotics on Weight Loss Maintenance in Individuals With Obesity

Norwegian University of Science and Technology1 site in 1 country76 target enrollmentNovember 16, 2017

ConditionsObesity

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Obesity
Sponsor: Norwegian University of Science and Technology
Enrollment: 76
Locations: 1
Primary Endpoint: body composition
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Weight loss maintenance is the biggest challenge in obesity management, with the majority of weight-reduced individuals experiencing weight regain. The intake of probiotics has been shown to help in weight loss, but its potential in maximizing weight loss maintenance remains unknown. Therefore, the main aim of this study is to investigate the impact of probiotic consumption on weight loss maintenance. Secondary aims are to investigate if the intake of probiotics influences gut microbiota, cardio-metabolic profile, appetite and inflammatory markers.

Registry

clinicaltrials.gov

Start Date

November 16, 2017

End Date

December 31, 2020

Last Updated

5 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Norwegian University of Science and Technology

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•class I or II obesity (30 kg/m2 \< BMI \> 40 kg/m2)
•weight stable (\<2 kg variation in weight within the last 3 months)
•not currently dieting to lose weight
•dietary intervention of 1000 kcal energy restriction for 8 weeks using a powder based low energy diet product, followed by 4 week weight stabilization phase (re-introduction of food)
•women who are either post-menopausal, taking oral contraceptives or with a normal cycle (28 ± 2 days)