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OB-GYN Clinical Validation Study

Not Applicable
Completed
Conditions
Obstetric Complication
GYN Disorders
Interventions
Device: Obstetrics and Gynecology clinical applications for ultrasound diagnostic systems
Registration Number
NCT06449872
Lead Sponsor
EchoNous Inc.
Brief Summary

This is a single-site study evaluating obstetrics and gynecology exam imaging quality by expert users.

Detailed Description

Six healthcare professionals with training and experience in Obstetrics and Gynecology ultrasound qualitatively assessed the image quality of the Kosmos Diagnostic Ultrasound System compared to the benchmark Mindray M9 Ultrasound System. Five sonographers were required to complete each scanning cohort of at least three gravid and three non-gravid participants. A sixth sonographer was added to the study to accommodate a scheduling conflict and provided additional image quality data outside of the five completed cohorts.

The following views/structures were assessed for image quality:

Gynecology participants:

* Uterus

* Ovaries

* Endometrial cavity

* Cervix

• Obstetrics participants in their 1st trimester:

* General image quality of the fetus

* Ability to visualize the crown rump length

* Visualization of gestational sac

* Visualization of yolk sac if present

• Obstetrics and participants in their 2nd trimester:

* General image quality of the fetal structures

* Visualization of the amniotic fluid

* Visualization of the placenta

* Cardiac motion in 2D and M-mode with heart rate

Obstetrics and participants in their 3rd trimester:

* General image quality of the fetal structures

* Visualization of the amniotic fluid

* Visualization of the placenta

* Visualization of the maternal cervix

* Cardiac motion in 2D and M-mode with heart rate

* 3 vessel umbilical cord in 2D and Color Doppler The sonographers captured all views/structures on the Mindray M9 Ultrasound System, then switched over to the Kosmos Diagnostic Ultrasound System to capture the same views/structures. Once all views/structures were captured on both ultrasound systems, the healthcare professionals reviewed the images in parallel on each system, then provided a comparison score for Kosmos between 1 and 7.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
44
Inclusion Criteria
  1. Persons able to:

    1. Read and sign an English consent form.
    2. Read and complete an English demographic and general health survey.
    3. Give consent for participation.
    4. Able and willing to comply with study requirements.
  2. Those aged 18 years through 40 years, healthy, particularly in respect to their pregnancy.

  3. Pregnant individuals who have received a previous ultrasound exam by their physician.

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Exclusion Criteria
  1. Children (minors) under 18 years old.
  2. Adults over 40 years old.
  3. Those who cannot or refuse to sign their consent.
  4. Those who cannot provide informed consent.
  5. Vulnerable populations, i.e., individuals whose willingness to participate in the study could be unduly influenced by the expectation of medical benefits associated with participation.
  6. Vulnerable populations, i.e., individuals whose willingness to participate in the study could be unduly influenced by parents, employer or monetary benefit.
  7. Pregnant individuals who have not received a previous ultrasound exam by their physician.
  8. Individuals who have had a hysterectomy, oophorectomy, and trachelectomy.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Comparison scanning protocol for OB and GYN clinical applicationsObstetrics and Gynecology clinical applications for ultrasound diagnostic systemsImage quality comparative assessment
Primary Outcome Measures
NameTimeMethod
Average Ultrasound Image Quality ScoreThrough study completion, up to 1 month

Qualitative image assessment of required views/structures generated with Kosmos Diagnostic Ultrasound System versus a cart-based ultrasound system.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

EchoNous, Inc.

🇺🇸

Redmond, Washington, United States

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